The Children's Cancer Center at City of Hope^® offers children, adolescents and young adults access to leading-edge care for a wide range of solid tumors and hematologic malignancies. Our nationally renowned team of physicians, researchers and support staff, based at our National Cancer Institute-designated comprehensive cancer center in Duarte, California, works together to ensure that each patient receives both personalized clinical care tailored to their unique diagnosis and the psychosocial support they need to transition from active treatment into survivorship and beyond. This personalized approach to pediatric care means that our childhood cancers team has maintained an 80% survival rate.

Some of the key benefits for patients receiving pediatric care at City of Hope include:

• Comprehensive molecular profiling, which allows physicians to identify biomarkers and genetic targets that may make treatment more effective for our youngest patients
• 24/7 inpatient pediatric intensive care coverage for patients receiving treatment at our comprehensive cancer center just outside Los Angeles
• Our stem cell and bone marrow transplant program, which is the largest and most successful in the nation, with more than 20,000 autologous and allogeneic transplants performed to date
• The Code Pediatrics Program, which expedites the transfer of patients aged 21 and under to our pediatric program at City of Hope Duarte within 24 hours
• Our Center for Gene Therapy, which conducts research into innovative new stem cell- and CAR T cell-based therapeutics for a wide range of hematologic malignancies
• Our Childhood, Adolescent and Young Adult Survivorship Program, one of only a few programs in the United States that provides late effects surveillance, risk-based care and technology-enabled follow-up care for pediatric patients throughout their lifetime
• Access to innovative clinical trials

The first step in diagnosing childhood cancer often takes place outside an oncology practice — and it can be overwhelming for both patients and their families. Our innovative Code Pediatrics program was created to expedite the transfer of pediatric patients to the Children’s Cancer Center at City of Hope within 24 hours of an initial referral. This ensures that referring physicians can offer their patients both expert consultation and seamless continuity of care. Referring clinicians can call our City of Hope Code Pediatrics line 24/7 for immediate consultation with a pediatric oncologist at (626) 256-HOPE (4673).

• Leukemia, including all types of acute and chronic disease
• Hodgkin and non-Hodgkin lymphoma • Musculoskeletal tumors, including osteosarcoma, Ewing sarcoma, chondrosarcoma, rhabdomyosarcoma and soft tissue sarcomas
• Brain tumors, including astrocytoma and medulloblastoma
• Reproductive system tumors
• Head and neck cancers, including oral, nasal, pharyngeal, sinus, thyroid and salivary gland cancers

As an academic center with a long history of developing breakthrough treatments for many different cancer types, City of Hope remains dedicated to conducting translational research that brings innovative therapies from the laboratory to patients’ bedsides as quickly as possible. In 2025 alone, researchers in the Childhood Cancer Center published 62 peer-reviewed articles on topics including survivorship outcomes, how treatment affects cardiovascular health and interactions between immunotherapies and T cell function.

Our pediatric cancer team at City of Hope Children’s Cancer Center includes medical, radiation and surgical oncologists and neuro-oncologists with expertise in all types and subtypes of childhood solid tumors and hematologic malignancies. The team also includes researchers focused exclusively on developing new ways to effectively detect and treat both pediatric solid tumors and blood cancers.

To refer a patient to City of Hope’s pediatric cancer experts, call 800-826-HOPE (4673) or email us at [email protected].