Clinical Trials at City of Hope

City of Hope® is a nationally recognized leader in cancer treatment and research. Every year, our national network of comprehensive cancer centers conducts more than 400 clinical trials that enroll more than 6,000 patients. Over the past 60 years, City of Hope has pioneered a wide range of basic and translational research projects that have led to groundbreaking cancer therapies, which are now standard of care for many cancer types.

Why Should You Refer Patients to a Clinical Trial at City of Hope?

City of Hope is the first academic cancer center with a national clinical trials program. By providing centralized support for referring physicians and their patients, our clinical trials program offers:

  • Greater access to novel therapies and potentially lifesaving care for more patients, no matter where they’re located
  • A more streamlined experience for doctors and patients when enrolling in a clinical trial at any City of Hope location
  • The ability to open new clinical trials to more patients more quickly and easily than ever
  • Fewer geographic or demographic barriers for patients who wish to enroll in a clinical trial

By offering clinical trials at our state-of-the-art cancer centers in Southern California, Phoenix, Atlanta and Chicago, we are able to bring breakthrough treatments to more patients.

If you're interested in referring a patient or a patient has requested information on clinical trials, use the selections below to explore our relevant clinical trials. If you have questions or want more information on signing up for a clinical trial, we're here to help, call (877) 405-2009.

Trial Status All Trial Statuses All Trial Statuses Open To Accrual Pending Suspended
Trial Location All Trial Locations All Trial Locations City of Hope Duarte City of Hope Atlanta City of Hope Chicago City of Hope Goodyear City of Hope Orange County Lennar Foundation Cancer Center City of Hope Antelope Valley City of Hope Arcadia City of Hope Arcadia Radiation Oncology City of Hope Corona City of Hope Downtown Chicago City of Hope Glendora City of Hope Long Beach Elm City of Hope Long Beach Worsham City of Hope Mission Hills City of Hope Newport Beach City of Hope Sand Canyon City of Hope Santa Clarita City of Hope Seacliff City of Hope South Bay City of Hope South Pasadena City of Hope Upland
Cancer Types All Cancer Types All Cancer Types Acute Leukemia Acute Lymphoblastic / Lymphocytic Leukemia Acute Lymphoblastic Leukemia Acute Myelogenous Leukemia Acute Myeloid Leukemia Acute Myeloid Leukemia (Aml) Acute Promyelocytic Leukemia Advanced / Metastatic Breast Cancer Advanced / Metastatic Solid Tumors Advanced Breast Cancer Advanced Epithelial Ovarian Cancer Advanced Hepatocellular Carcinoma Advanced Malignant Squamous Tumors Advanced Solid Tumors Advanced Solid Tumors Expected To Express Ib6 All Locally Advanced Or Metastatic Solid Tumors All Solid Tumors Allogeneic Hematopoietic Cell Transplantation Allogeneic Hematopoietic Stem-Cell Transplantation Allogeneic Stem Cell Transplantation Allogenic Hematopoietic Stem Cell Transplant Amyloid Light-Chain (Al) Amyloidosis Appendiceal Metastasis Astrocytomas Autologous Hematopoietic Cell Transplantation B Cell Malignancies B Cell Precursor Acute Lymphoblastic Leukemia B-Cell Acute Lymphoblastic Leukemia B-Cell Lymphoma B-Cell Lymphomas B-Cell Malignancies B-Cell Non-Hodgkin Lymphoma Basal Cell Carcinoma Be Cell Non-Hodgkin Lymphoma Biliary Tract Cancer Biliary Tract Carcinoma Bladder Cancer Bone Marrow Biopsy Bone Marrow Transplant Bone Metastasis Brain Metastasis Breast Cancer Cancer Cancer Survivors Candidemia Cell Transplantation Cellular Therapy Cervical Cancer Chronic Graft-Versus-Host Disease Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma Chronic Myeloid Leukemia Chronic Myelomonocytic Leukemia Classical Hodgkin Lymphoma Clear Cell Renal Cell Carcinoma Colon Cancer Colorectal Cancer Colorectal Carcinoma Colorectal Metastasis Crc Cutaneous Squamous Cell Carcinoma Cytotoxic Lymphomas Dcis Breast Cancer Diabetes Diffuse Large B-Cell Lymphoma Diffuse Large B-Cell Lymphoma (Dlbcl) Dlbcl Early Breast Cancer Early Stage Breast Cancer Endometrial Endometrial Cancer Endometrial Carcinoma Esophageal Cancer Esophageal Squamous Cell Carcinoma Ewing Sarcoma Extrapulmonary Neuroendocrine Carcinomas Fallopian Tube Cancer Fl Follicular Lymphoma Gastric Adenocarcinoma Gastric Cancer Gastroesophageal Cancer Gastroesophageal Junction Cancer Gastrointestinal Cancer Gastrointestinal Stromal Tumors Gc / Gejc Germ Cell Tumors Glioblastoma Gynecological Cancer Head & Neck Squamous Cell Carcinoma Head And Neck Cancer Head And Neck Squamous Cell Carcinoma Healthy Volunteers Hematologic Malignancies Hematologic Malignancy Hematological Malignancies Hematopoietic Cell Transplantation Hematopoietic Stem Cell Transplant Hematopoietic Stem Cell Transplantation Hepatocellular Cancer Hepatocellular Carcinoma Her2+ Advanced Breast Cancer High-Grade B-Cell Lymphoma High-Risk Acute Leukemia High-Risk Myelodysplastic Syndrome Hnscc Hodgkin Lymphoma Hr+ Advanced Breast Cancer Infectious Disease Infusion Therapy Nausea Infusion-Based Treatment Anxiety Islet Transplantation Kras Mutation Kras+ Advanced Colorectal Cancer Kras+ Nsclc Large Granular Lymphocytic Leukemia Leptomeningeal Disease Light Chain Amyloidosis Locally Advanced / Metastatic Solid Tumors Locally Advanced Breast Cancer Lower Respiratory Tract Parainfluenza Infection Lung Cancer Lymphoblastic Lymphoma Lymphocytic Leukemia Lymphoma Lymphoplasmacytic Lymphoma Mantle Cell Lymphoma Marginal Zone Lymphoma Melanoma Merkel Cell Cancer Metastatic Breast Cancer Metastatic Castration-Resistant Prostate Cancer Metastatic Or Unresectable Solid Tumors Metastatic Prostate Cancer Multiple Myeloma Myelodysplastic Syndrome Myelodysplastic Syndromes Myelodysplastic Syndromes (Mds) Myelofibrosis Myeloid Leukemia Myeloid Malignancies Myeloproliferative Neoplasm Myeloproliferative Neoplasms Non-Advanced Adenomatous Polyps Non-Advanced Tubular Adenomas Non-Hodgkin’S Lymphoma Non-Small Cell Lung Cancer Non-Small Lung Cancer Nsclc Oligo-Progressive Non-Small Cell Lung Cancer Oral Cavity Cancer Oropharyngeal Cancer Ovarian Ovarian Cancer Pancreatic Cancer Pancreatic Ductal Adenocarcinoma Peripheral Blood Stem Cell Transplantation Peritoneal Cancer Post–Essential Thrombocythemia Myelofibrosis Post–Polycythemia Vera Myelofibrosis Prefibrotic Myelofibrosis Primary Myelofibrosis Prostate Cancer Rectal Cancer Recurrent Breast Cancer Relapsed / Refractory Hematologic Malignancies Relapsed / Refractory Multiple Myeloma Renal Cancer Renal Cell Carcinoma Respiratory Syncytial Virus Infection Sarcoma Sclc Severe Aplastic Anemia Small Cell Lung Cancer Small Lymphocytic Lymphoma Solid Tumor Solid Tumors Solid Tumors With Msi H / Dmmr Histology Squamous Cell Carcinoma Squamous Cell Carcinoma Of Penile, Anal, Vaginal, Vulvar, Cervical And Urethral Squamous Cell Carcinoma Of The Head And Neck Squamous Cell Carcinoma Of The Lung Squamous Cell Carcinoma Of The Tongue Squamous Cell Carcinomas Of The Head And Neck Squamous Cell Non-Small Cell Lung Cancer Stage I And Ii Classic Hodgkin Lymphoma Stage Ii-Iii Breast Cancer Stomach Cancer Systemic Mastocytosis T-Cell Acute Lymphoblastic Leukemia T-Cell Lymphoblastic Lymphoma T-Cell Lymphoproliferative Neoplasms Thrombocytopenia Thyroid Cancer Thyroid Nodules Transfusion Dependent Anemia Transfusion-Dependent A-Or B-Thalassemia Unilateral Favorable Histology Wilms Tumors Urothelial / Transitional Cell Or Pure Squamous Cell Carcinoma Of The Bladder Urothelial Cancer Uterine Cancer Waldenström Macroglobulinemia Waldenström Macroglobulinemia / Lymphoplasmacytic Lymphoma Waldenström's Macroglobulinemia Waldenström’S Macroglobulinemia Warm Autoimmune Hemolytic Anemia