City of Hope

Breast Cancer Program

Accelerating Access to Leading-Edge Breast Cancer Treatment for More Arizonans

About Our Program

City of Hope® Cancer Center Phoenix, with four locations across the Valley, provides multidisciplinary care to diagnose and treat all types and stages of breast cancer. Our program offers patients the specialty care they deserve from diagnosis through survivorship, with physicians who specialize in early and advanced stage breast cancer. Additionally, we offer a high-risk breast cancer program to individualize risk profiles and provide optimal strategies for early detection.

Our program provides a uniquely personalized, leading-edge cancer care experience for our patients, including:

  • Access to a multidisciplinary team comprised of experts in breast cancer, including surgeons, medical and radiation oncologists, interventional radiologists, supportive care team members and more
  • Advanced surgical techniques such as nipple-sparing mastectomy and microsurgical options for immediate or delayed reconstruction
  • An established precision medicine program that incorporates genetic sequencing and profiling of primary tumors to determine strategic targeted therapies or clinical trial opportunities
  • Access to groundbreaking clinical trials involving novel drugs and leading therapies
  • A supportive care and survivorship program for patients and their loved ones
  • Access to the nation’s top subspecialists through disease-specific weekly cancer conferences, to provide information sharing and optimize therapeutic options for patients

Referral Request Form

Referring physicians can speak directly with a City of Hope specialist to discuss patient care or make a referral.

Meet Our Experts

Our program is comprised of a multidisciplinary team of experts specializing in breast cancer, including surgeons, medical and radiation oncologists, interventional radiologists, supportive care team members and more. Several of our physicians hold faculty positions within City of Hope and externally and have obtained unique certifications.

Cynthia Lynch -Medical Director of Breast Center, Medical Oncologist

Cynthia Lynch, M.D.

Medical Director of Breast Program
Medical Oncologist
Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research

Cynthia Lynch, M.D., joined City of Hope Phoenix in 2015. In her role as a medical oncologist, Dr. Lynch exclusively focuses her practice on the clinical management of breast cancer. As part of the Women’s Cancer Center at City of Hope Phoenix, Dr. Lynch works with a multidisciplinary team of specialists dedicated to cancers that affect women, including breast and gynecologic malignancies. During her career she has led numerous clinical trials, with focuses on breast malignancies, including several focused on advanced breast cancer treatments.

Linda Ling-Ying Liu, M.D.

Breast Surgeon
Associate Clinical Professor, Department of Surgery

Linda Ling-Ying Liu, M.D., is a board-certified breast cancer surgeon at City of Hope Care Center Scottsdale and City of Hope Cancer Center Phoenix. With more than 20 years’ experience in her field and a collaborative approach to care, Dr. Liu is dedicated to working closely with patients to ensure they receive innovative, compassionate care and superior aesthetic results.

Raquel Prati -  Breast Surgeon

Raquel Prati, M.D.

Breast Surgeon
Associate Clinical Professor, Department of Surgery

Raquel Prati, M.D., joined City of Hope Phoenix in July of 2017. In her role as a breast surgeon at City of Hope Phoenix, Dr. Prati performs breast surgery, including lumpectomies and mastectomies, offering minimally invasive options whenever possible. She has extensive experience in skin- sparing and nipple-sparing techniques, which allow for immediate reconstruction by a plastic surgeon. Dr. Prati works with a multidisciplinary team of dedicated breast cancer specialists to meet the needs of her patients who require additional treatment before or after surgery.

Zoe-MacIsaac-PHX

Zoe MacIsaac, M.D.

Plastic Surgeon

Zoe MacIsaac, M.D., joined City of Hope in 2019. As a plastic surgeon at City of Hope Phoenix, Dr. MacIsaac focuses her practice on breast cancer reconstruction, as well as complex reconstruction of the head and neck, the extremities and other areas. She performs primary and secondary breast reconstruction after mastectomy, including reconstruction following nipple-sparing mastectomy and reconstruction after lumpectomy, including oncoplastic rearrangement and oncoplastic breast reduction. Dr. MacIsaac’s techniques are tailored to each individual patient and ranges from autologous fat transfer to tissue expander and implant-based reconstruction. In addition, she performs completely autologous procedures using only the patient’s own tissue during breast reconstruction and repairs nerve endings following mastectomy to give patients chance to regain sensation.

LaNette F. Smith, M.D.

Breast Surgical Oncologist
Associate Clinical Professor, Department of Surgery

LaNette F. Smith, M.D., joined City of Hope in 2026. As a breast surgeon, Dr. Smith works closely with patients diagnosed with multiple types and stages of breast cancer, offering both conventional and less invasive surgical treatment options, including nipple sparing mastectomy and image guided breast biopsy. Throughout her career, she has cared for patients across Arizona, providing individualized surgical care grounded in expertise and compassion.

Refer a Patient to City of Hope

We strive to offer a well-coordinated experience to our referring providers. Upon receiving your referral, our team will immediately begin processing it, with minimal work on your end.

Please select a location City of Hope Phoenix City of Hope Gilbert City of Hope North Phoenix City of Hope Prescott City of Hope Scottsdale
Address

14200 West Celebrate Life Way
Goodyear, AZ 85338

Contact information

Phone: (623) 207-3241

Fax: (623) 932-8631

Email: [email protected]

Address

3530 S. Val Vista Drive
Suite C204
Gilbert, AZ 85297

Contact information

Phone: (623) 207-3241

Fax: (623) 932-8631

Email: [email protected]

Address

2915 W. Rose Garden Lane
Phoenix, AZ 85027

Contact information

Phone: (623) 207-3241

Fax: (623) 932-8631

Email: [email protected]

Address

5430 Landmark Lane
Prescott AZ 86301

Contact information

Phone: (623) 207-3241

Fax: (623) 932-8631

Email: [email protected]

Address

20159 N Scottsdale Rd., Suite 100
Scottsdale, AZ 85255

Contact information

Phone: (623) 207-3241

Fax: (623) 932-8631

Email: [email protected]

Institutional Distinctions

Led by a more than 100-year pacesetter in treating life-threatening diseases, including breast cancer, our national network:

  • Surpasses Surveillance, Epidemiology, and End Results (SEER) Program national median survival rates for female breast cancer at all stages
  • Provides access to over 100 breast cancer clinical trials
  • Employs over 40 breast cancer experts
  • Developed monoclonal antibody technology used to create breakthrough cancer drugs, including Herceptin® to treat HER2+ breast cancer
  • Offers an accelerated bench-to-bedside approach with three Good Manufacturing Practices (GMP)-certified facilities at our core
  • Is a pioneer in the application of robotic-assisted, single-incision mastectomies for breast cancer

Our Services and Offerings

At City of Hope, our clinical experts all have one collective goal, to treat cancer with precision and compassion so our patients can get back to living their lives. 

We offer a comprehensive range of services, including:

  • Breast cancer surgery
  • Breast reconstruction
  • Research/clinical trials
  • Fertility evaluation
  • High-risk surveillance and prophylactic treatment
  • Genetic counseling and testing
  • Genomic profiling
  • Medical oncology
  • Pathology
  • Radiation therapy
  • Survivorship
  • Supportive care services, including nutritional support, physical therapy, behavioral health services, etc.

Treatment offerings may vary by location.

Our Commitment to Clinical Excellence

City of Hope Cancer Center Phoenix, located in Goodyear, is recognized by several organizations that evaluate the quality of breast cancer programs as:

  • An accredited breast center by the National Accreditation Program for Breast Cancer (NAPBC), granted to facilities that provide the best possible care to patients with diseases of the breast
  • A Surgical Quality Partner, a distinction earned through the American College of Surgeon's quality program, which was awarded through our participation in NAPBC
  • A Designated Comprehensive Breast Imaging Center by the American College of Radiology, with full accreditation in mammography, stereotactic breast biopsy, breast ultrasound, ultrasound-guided breast biopsy and breast MRI
  • A program accredited by the American Society of Radiation Oncology's Accreditation Program For Excellence® for providing high quality and safe radiation oncology care to patients
  • Meeting the highest standards for quality cancer care by the Quality Oncology Practice Initiative Certification Program, an affiliate of the American Society of Clinical Oncology
  • An accredited facility for nearly four decades by the American College of Surgeons Commission on Cancer for excellence in providing quality care to cancer patients

Additionally, several of our physicians hold faculty positions both within City of Hope and externally have obtained unique certifications or fellowship training specifically for breast cancer.

The entire breast cancer team works in a multidisciplinary care environment and participates in regularly scheduled breast cancer tumor boards with experts from across the City of Hope national cancer system, ensuring patients receive the best treatment options available.

Latest Breast Cancer News

June 12, 2026 | By City of Hope
City of Hope Phoenix Expands Surgical Oncology Care Options
December 01, 2025 | By Tania Cortas
Arizona Mammography Screening Rates Trail National Benchmark
November 06, 2025 | By City of Hope
Screening Mammograms Key to Addressing Rising Breast Cancer Rates in Younger Women - City of Hope Cancer Center Phoenix

Dedication to Speed to Care

City of Hope Cancer Center and our outpatient locations are intentionally structured to maximize speed to care, with:

Appointments available in as little as 24 hours and treatment within one week or less
Two- to four-hour radiology turnaround
48-hour pathology turnaround